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Chromosome Aberrations --- Testicular Neoplasms --- Neoplasms, Germ Cell and Embryonal --- genetics
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Neoplasms, Germ Cell and Embryonal --- Testicular Neoplasms --- surgery --- surgery
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Testicular Neoplasms --- alpha-Fetoproteins --- Chorionic Gonadotropin --- Neoplasms, Germ Cell and Embryonal --- enzymology --- biosynthesis --- blood
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Cell Differentiation --- Cisplatin --- Neoplasms, Germ Cell and Embryonal --- Etoposide --- Neoplasms --- drug effects --- pharmacology --- chemistry --- pharmacology --- drug therapy
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Neoplasms, Germ Cell and Embryonal --- Biomarkers, Tumor --- Cisplatin --- Testicular Neoplasms --- Tumor Suppressor Protein p53 --- diagnosis --- analysis --- therapeutic use --- drug therapy
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Epidermal Cell Tumors: The Basics serves as an effective and efficient handbook for the student of dermatopathology, and as a practical bench reference for the practicing diagnostician who desires rapid access to criteria that are useful in differentiating histologically similar entities. The chapters consist of essential bullet points arranged in organized outlines allowing for easy access and direct comparison between entities. The elaborate pictorial documentation enables the book to serve as an atlas of the most common dermatologic disorders.
Dermatology. --- Melanoma. --- Skin -- Cancer. --- Skin Neoplasms. --- Neuroendocrine Tumors --- Nevi and Melanomas --- Neoplasms by Site --- Skin Diseases --- Neoplasms --- Skin and Connective Tissue Diseases --- Neuroectodermal Tumors --- Neoplasms by Histologic Type --- Melanoma --- Skin Neoplasms --- Diseases --- Neoplasms, Nerve Tissue --- Neoplasms, Germ Cell and Embryonal --- Medicine --- Health & Biological Sciences --- Pathology --- Oncology --- Epidermis --- Skin --- Tumors. --- Cancer. --- Medicine. --- Pathology. --- Medicine & Public Health. --- Epithelium --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive
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This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches. The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.
Medicine & Public Health. --- Gastroenterology. --- Endocrinology. --- Oncology. --- Diagnostic Radiology. --- Medicine. --- Radiology, Medical. --- Médecine --- Endocrinologie --- Gastroentérologie --- Cancérologie --- Neuroendocrine tumors --- Digestive System Neoplasms --- Neuroectodermal Tumors --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms, Germ Cell and Embryonal --- Neoplasms by Site --- Neoplasms by Histologic Type --- Neoplasms --- Diseases --- Pancreatic Neoplasms --- Neuroendocrine Tumors --- Diagnosis --- Medicine --- Health & Biological Sciences --- Gastroenterology --- Chemotherapy. --- Radiology. --- Tumors --- Oncology . --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Internal medicine --- Digestive organs --- Hormones --- Gastroenterology . --- Endocrinology . --- Radiological physics --- Physics --- Radiation
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Highly acclaimed and considered the leading reference in the field, Pathology of Melanocytic Nevi and Melanoma has once again been fully revised, updated, and expanded to reflect the most recent advances and techniques in the field of melanoma pathology. New chapters on mucosal melanoma, ocular melanoma, and pigmented lesions of the nail apparatus have been included in this new edition. The successful focus and format of the previous editions have been preserved. Each lesion and diagnosis is clearly illustrated with the aid of a wealth of digitally enhanced full-color photomicrographs. A concise description of the clinical features, histopathology, differential diagnosis, and outstanding characteristics of each lesion provides readers with a quick yet comprehensive overview of each topic covered. Pathology of Melanocytic Nevi and Melanoma is the essential reference for every practicing dermatopathologist, pathologist, dermatologist, and cancer research scientist today.
Dermatology. --- Medicine. --- Melanoma -- Pathophysiology. --- Melanoma. --- Oncology. --- Pathology. --- Skin Diseases --- Neoplasms by Site --- Nevi and Melanomas --- Neuroendocrine Tumors --- Epithelial Cells --- Neoplasms by Histologic Type --- Neuroectodermal Tumors --- Cells --- Neoplasms --- Skin and Connective Tissue Diseases --- Diseases --- Anatomy --- Neoplasms, Nerve Tissue --- Neoplasms, Germ Cell and Embryonal --- Skin Neoplasms --- Melanoma --- Melanocytes --- Nevus --- Medicine --- Health & Biological Sciences --- Oncology --- Pathophysiology. --- Malignant melanoma --- Melanocytic tumor --- Medicine & Public Health. --- Cancer --- Neuroendocrine tumors --- Oncology . --- Tumors --- Skin --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive
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Treatment of glioma is currently one of the most challenging problems in oncology, as well as in neurosurgery. Despite major advances in our understanding of the pathomechanism, diagnosis by imaging and the availability of powerful therapeutic tools, the life expectancy of patients with glioblastoma has only been slightly prolonged and a cure remains elusive. None of the currently available surgical tools, including operative microscopes, lasers and image-guided surgery, can enable the detection and removal of all of the tumor tissue. In recent years, however, the landscape has been changing immeasurably, and molecular studies over the past two decades have identified a variety of genetic aberrations that are specifically associated with individual types of gliomas. In addition, certain molecular abnormalities have been linked to therapy responses, thereby establishing clinical biomarkers and molecular targets, and the use of novel agents is being investigated. These agents have been specifically engineered to exert specific cytotoxicity against gliomas, either on their own as single agents or in combination with other modalities. Moreover, there has been an enormous surge of interest in the area of immunology and immunotherapy, which has been facilitated by our understanding of the molecular basis of gliomas. Although several kinds of immunotherapeutic trials have been undertaken, we still await a great breakthrough in terms of clinical efficacy to prolong the survival time of glioma patients.
Gliomas -- Immunotherapy. --- Gliomas. --- Investigative Techniques --- Immunomodulation --- Neoplasms, Neuroepithelial --- Neuroectodermal Tumors --- Biological Therapy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms, Glandular and Epithelial --- Neoplasms by Histologic Type --- Therapeutics --- Neoplasms, Germ Cell and Embryonal --- Neoplasms, Nerve Tissue --- Neoplasms --- Diseases --- Glioma --- Immunotherapy --- Methods --- Medicine --- Health & Biological Sciences --- Oncology --- Gliomas --- Treatment. --- Medicine. --- Cancer research. --- Immunology. --- Biomedicine. --- Biomedicine general. --- Cancer Research. --- Immunobiology --- Life sciences --- Serology --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Nervous system --- Tumors --- Oncology. --- Health Workforce --- Biomedicine, general.
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Gliomas, which comprise astrocytic, oligodendroglial, and ependymal lesions, are the most frequent primary intracranial tumors. This volume summarizes the enormous advances in our knowledge of gliomas that have occurred during recent years. The first part of the book focuses on the glial tumor entities, with detailed discussion of diagnosis, molecular genetics, and tumor origin. This section also contains a chapter on hereditary tumor syndromes associated with gliomas and the molecular mechanisms underlying these specific diseases. The second part is devoted to the clinical management of gliomas and provides insights into novel developments regarding neuroimaging, surgical management, radiation therapy, adjuvant therapy, experimental approaches, and the neurotoxicity of treatment. The final part of the book addresses angiogenesis and epigenetic regulation of gene expression in gliomas.
Gene therapy. --- Glioma. --- Gliomas. --- Medicine. --- Nervous system. --- Neurology. --- Oncology. --- Gliomas --- Neoplasms, Neuroepithelial --- Biological Therapy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Therapeutics --- Neoplasms, Glandular and Epithelial --- Neuroectodermal Tumors --- Neoplasms, Nerve Tissue --- Neoplasms, Germ Cell and Embryonal --- Neoplasms by Histologic Type --- Neoplasms --- Diseases --- Gene Therapy --- Glioma --- Diagnosis --- Medicine --- Health & Biological Sciences --- Oncology --- Nervous system --- Tumors. --- Neurosurgery. --- Medicine & Public Health. --- Nerves --- Neurosurgery --- Neuropsychiatry --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Surgery
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