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Dissertation
Pathogenesis of testicular germ cell tumors : a cytogenetical and pathological study.
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Year: 1988 Publisher: Groningen Van Denderen

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Dissertation
Surgery in the treatment of nonseminomatous testicular tumors
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Year: 1987 Publisher: Groningen Van Denderen

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Dissertation
Nonseminomatous germ cell tumors of the testis.
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Year: 1984 Publisher: Groningen Van Denderen

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Dissertation
Modulation of cisplatin activity and toxicity : changing the drug or changing the target
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Year: 1993 Publisher: S.l. s.n.

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Dissertation
Role of apoptotic pathways in chemosensitivity of testicular germ cell tumours.
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Year: 2009 Publisher: S.l. s.n.

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Book
Epidermal Cell Tumors: The Basics
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ISBN: 1441977031 9786612971945 144197704X 1282971948 Year: 2011 Publisher: New York, NY : Springer US : Imprint: Springer,

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Epidermal Cell Tumors: The Basics serves as an effective and efficient handbook for the student of dermatopathology, and as a practical bench reference for the practicing diagnostician who desires rapid access to criteria that are useful in differentiating histologically similar entities. The chapters consist of essential bullet points arranged in organized outlines allowing for easy access and direct comparison between entities. The elaborate pictorial documentation enables the book to serve as an atlas of the most common dermatologic disorders.


Book
Management of Pancreatic Neuroendocrine Tumors
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ISBN: 9781493917983 1493917978 9781493917976 1493917986 Year: 2015 Publisher: New York, NY : Springer New York : Imprint: Springer,

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This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches. The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.


Book
Pathology of Melanocytic Nevi and Melanoma
Authors: --- ---
ISBN: 364238384X 3642383858 Year: 2014 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Highly acclaimed and considered the leading reference in the field, Pathology of Melanocytic Nevi and Melanoma has once again been fully revised, updated, and expanded to reflect the most recent advances and techniques in the field of melanoma pathology. New chapters on mucosal melanoma, ocular melanoma, and pigmented lesions of the nail apparatus have been included in this new edition. The successful focus and format of the previous editions have been preserved. Each lesion and diagnosis is clearly illustrated with the aid of a wealth of digitally enhanced full-color photomicrographs. A concise description of the clinical features, histopathology, differential diagnosis, and outstanding characteristics of each lesion provides readers with a quick yet comprehensive overview of each topic covered. Pathology of Melanocytic Nevi and Melanoma is the essential reference for every practicing dermatopathologist, pathologist, dermatologist, and cancer research scientist today.


Book
Glioma : Immunotherapeutic Approaches
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ISBN: 146143145X 9786613696991 1461431468 1280786604 Year: 2012 Publisher: New York, NY : Springer New York : Imprint: Springer,

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Treatment of glioma is currently one of the most challenging problems in oncology, as well as in neurosurgery. Despite major advances in our understanding of the pathomechanism, diagnosis by imaging and the availability of powerful therapeutic tools, the life expectancy of patients with glioblastoma has only been slightly prolonged and a cure remains elusive. None of the currently available surgical tools, including operative microscopes, lasers and image-guided surgery, can enable the detection and removal of all of the tumor tissue. In recent years, however, the landscape has been changing immeasurably, and molecular studies over the past two decades have identified a variety of genetic aberrations that are specifically associated with individual types of gliomas. In addition, certain molecular abnormalities have been linked to therapy responses, thereby establishing clinical biomarkers and molecular targets, and the use of novel agents is being investigated. These agents have been specifically engineered to exert specific cytotoxicity against gliomas, either on their own as single agents or in combination with other modalities. Moreover, there has been an enormous surge of interest in the area of immunology and immunotherapy, which has been facilitated by our understanding of the molecular basis of gliomas. Although several kinds of immunotherapeutic trials have been undertaken, we still await a great breakthrough in terms of clinical efficacy to prolong the survival time of glioma patients.


Book
Gliomas
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ISBN: 3540312056 9786612068423 1282068423 3540312064 Year: 2009 Publisher: Berlin : Springer,

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Gliomas, which comprise astrocytic, oligodendroglial, and ependymal lesions, are the most frequent primary intracranial tumors. This volume summarizes the enormous advances in our knowledge of gliomas that have occurred during recent years. The first part of the book focuses on the glial tumor entities, with detailed discussion of diagnosis, molecular genetics, and tumor origin. This section also contains a chapter on hereditary tumor syndromes associated with gliomas and the molecular mechanisms underlying these specific diseases. The second part is devoted to the clinical management of gliomas and provides insights into novel developments regarding neuroimaging, surgical management, radiation therapy, adjuvant therapy, experimental approaches, and the neurotoxicity of treatment. The final part of the book addresses angiogenesis and epigenetic regulation of gene expression in gliomas.

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